By E. J. Ariëns
The publication discusses the modulation of pharmacokinetics through molecular manipulation; the criteria within the layout of reversible and irreversible enzyme inhibitors; and the layout of organophosphate and carbamate inhibitors of cholinesterases. The textual content additionally describes the layout of reactivators for irreversibly blocked acetylcholinesterase; drug layout in keeping with the inhibition of protein synthesis within the context of vulnerable enzymic reactions; in addition to the function of enzymes and their synthesis as a aim for antibiotic motion. The rational layout of antiviral brokers; the layout of penicillin; the layout of peptide hormone analogs; in addition to the advances within the layout of diuretics also are thought of. The ebook additional tackles the layout of biologically lively steroids; the rational parts within the improvement of better neuromuscular blockading brokers; and the layout of tumor-inhibitory alkylating medicines.
Pharmacologists, chemists, and other people concerned with drug layout will locate the ebook invaluable.
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Drug Design: Medicinal Chemistry: A Series of Monographs, Vol. 2 by E. J. Ariëns