Download PDF by Arun K. Ghosh,Sandra Gemma: Structure-based Design of Drugs and Other Bioactive

By Arun K. Ghosh,Sandra Gemma

Drug layout is a posh, tough and leading edge examine zone. Structure-based molecular layout has remodeled the drug discovery technique in glossy medication. characteristically, concentration has been put on computational, structural or man made tools in simple terms in isolation. This one-of-akind consultant integrates all 3 ability units for a whole photograph of up to date structure-based design.

This functional method presents the instruments to enhance a high-affinity ligand with drug-like homes for a given drug aim for which a high-resolution constitution exists. The authors use quite a few examples of lately constructed medications to give "best perform" tools in structurebased drug layout with either beginners and training researchers in brain. when it comes to a delicately balanced mixture of theoretical historical past and case reports from medicinal chemistry functions, readers will quick and successfully grasp the fundamental abilities of winning drug design.

This ebook is geared toward new and energetic medicinal chemists, biochemists, pharmacologists, usual product chemists and people operating in drug discovery within the pharmaceutical undefined. it really is hugely steered as a table connection with consultant scholars in medicinal and chemical sciences in addition to to assist researchers engaged in drug layout today.

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Structure-based Design of Drugs and Other Bioactive Molecules: Tools and Strategies by Arun K. Ghosh,Sandra Gemma


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