Genomic Perl: From Bioinformatics Basics to Working Code - download pdf or read online

By Rex A. Dwyer

This creation to computational molecular biology might help programmers and biologists study the abilities had to commence paintings during this vital, increasing box. the writer explains some of the easy computational difficulties and offers concise, operating courses to resolve them within the Perl programming language. With minimum must haves, the writer explains the organic historical past for every challenge, develops a version for the answer, then introduces the Perl strategies had to enforce the answer. The booklet covers pairwise and a number of series alignment, quickly database searches for homologous sequences, protein motif identity, genome rearrangement, actual mapping, phylogeny reconstruction, satellite tv for pc id, series meeting, gene discovering, and RNA secondary constitution. The concrete examples and step by step procedure make it effortless to know the computational and statistical tools, together with dynamic programming, branch-and-bound optimization, grasping tools, greatest probability equipment, substitution matrices, BLAST looking, and Karlin-Altschul records. Perl code is supplied at the accompanying CD.

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